Mal-amido-PEG24-NHS ester
Sulfhydryl-specific discrete PEG linkers featuring Maleimide (Mal), OPSS (pyridyldithiol), and bromoacetamide (-Br) for alkylation. A core skeleton for antibody-payload linking in ADC synthesis.
Monodisperse PEG scaffolds for primary amine modification, including active NHS, TFP, and PFP esters, plus terminal -COOH (carboxylic acid). Used for antibody and peptide PEGylation.
Technical Data
| CAS Number | 2226733-37-3 |
| MDL Number | MFCD11041160 |
| Item Number | LK30324 |
| Molecular Formula | C62H111N3O31 |
| Molecular Weight | 1394.55 |
| Purity | ≥95.0% |
| Appearance | Solid |
| Color | White to off-white |
| Packages | 100mg,1g,5g,Bulk |
| Storage Conditions | Store at -20℃, keep desiccated and protected from light |
| SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O |
| Synonyms | Maleimide-NH-PEG24-CH2CH2COONHS Ester;alpha-Maleinimido-24(ethylen glycol-omega-propionic acid succinimidyl ester;2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76-tetracosaoxa-4-azanonaheptacontan-79-oate |
Description
Monodisperse PEG Linkers for Bioconjugation & Therapeutics Research
Synthenera offers a broad selection of discrete (monodisperse) PEG linkers developed for antibody-drug conjugates (ADCs), PROTAC discovery, peptide synthesis, and click chemistry applications. Our monodisperse PEG linkers feature a defined chain length and precise molecular weight, helping researchers reduce batch variation compared to standard polydisperse polymers. We focus on single-isomer purity to help minimize unpredictable cross-linking or structural impurities in early-stage development and process scale-up.
Reliable Source & Flexible Scale Supply Solutions
As a specialized provider and original source of functionalized PEG derivatives, Synthenera supports your pipeline from initial laboratory screening to pilot scale-up. We provide flexible supply capacities, offering multi-gram quantities for high-throughput discovery up to multi-kilogram batches for process optimization. By shipping directly from our centralized repository, we are able to provide competitive direct pricing and efficient technical support to help you manage your research budget.
Traceable Quality Control & Essential Documentation
We recognize that data transparency is essential for biotechnology research and regulatory evaluation. Every batch supplied by Synthenera undergoes essential chemical analysis to verify identity and purity. We supply standard analytical documentation with each shipment, including:
- Certificate of Analysis (COA) outlining verified batch specifications.
- High-Performance Liquid Chromatography (HPLC) / Gas Chromatography (GC) profiles to confirm chemical and structural purity (typically ≥ 95% or ≥ 98%).
- Nuclear Magnetic Resonance (NMR) & Mass Spectrometry (MS) data confirming the correct molecular structure.
Custom Packaging & Tailored Solutions
To meet different experimental requirements, Synthenera offers flexible custom packaging, bulk pricing discounts, and custom synthesis services for specific functional groups, protected intermediates, or custom PEG lengths.
For inquiries regarding bulk volume pricing, lead times, or customized synthesis requests, please reach out to our team at: sales@synthenera.com.
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